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Wednesday, May 21, 2008

Large Hadron Collider is gearing up to slam protons together at energies that have not yet been studied on Earth.

A visitor snaps a picture of the Large Hadron Collider's underground beamline during an open house in April, which was the last opportunity for the public to see the facility before the scheduled start of operations.
BIG-BANG BATTLE PLAN SET

The schedule is taking shape for the startup of the world's biggest particle-smasher — and for the lawsuit seeking to shut it down.
The plaintiffs in that lawsuit have served the federal government with a summons, and Justice Department lawyers are due to respond by June 24. One of the other parties in the case, Europe’s CERN particle-physics center, is supposed to be served this week in Switzerland, according to Walter Wagner, one of the plaintiffs.
CERN's Large Hadron Collider is gearing up to slam protons together at energies that have not yet been studied on Earth. The peak energy of 14 trillion electron volts approaches levels seen in the first microseconds after the big bang - which is why the collider has been nicknamed the "Big Bang Machine."
Wagner and his co-plaintiff, Luis Sancho, are worried that when the collider reaches full power, it could create black holes or strangelets that would grow and gobble up our planet.
Physicists at CERN and the world's other top-level research facilities have been saying for years that that's mere science-fiction silliness. Nevertheless, Wagner, Sancho and other critics continue to sound the alarm. They want operations at the collider to be put on hold for at least four months, pending further safety reviews that would address the black-hole question and other potential risks.
Among other defendants, the lawsuit names the U.S. Department of Energy, the National Science Foundation and Fermilab in Illinois, the laboratory that is playing the lead U.S. role in the Large Hadron Collider. The Justice Department is handling the federal government's legal response, and Justice spokesman Andrew Ames said he would not comment on the suit until the response is filed next month.
Federal attorneys are likely to focus their defense on relatively narrow legal issues – for example, claiming that the government as well as government-funded scientists have complied with environmental guidelines, or that the LHC project is not subject to U.S. regulations, or that the lawsuit should be thrown out because of technicalities. That’s how Wagner’s challenges to previous particle-collider experiments have been handled.
Although anything can happen (even the sudden eruption of a rogue black hole in the courtroom), I wouldn’t expect the attorneys’ brief to focus on the globe-gobbling question. That element of the controversy will be addressed in a safety report currently being reviewed by CERN and outside experts. The report, which is said to underline and amplify previous conclusions that the LHC is safe, could be released by the end of this month, CERN spokesman James Gillies told me.
The technical report is currently undergoing a final review by CERN’s scientific policy committee as well as outside experts, and Gillies is writing up a version in easier-to-understand language for the benefit of us non-physicists.
First beams in July?Meanwhile, CERN’s startup schedule is coming into better focus as well: The LHC team is due to start cooling down the last sectors of the collider’s beamline to near absolute zero on Wednesday, with the expectation that cooldown will be complete by mid-June, Gillies said. That would clear the way for a final round of equipment testing, with the first attempt to inject proton beams into the collider “likely to be in the second half of July,” he said.
The exact date would be set four to six weeks in advance – leaving enough time to plan a big media event around the first beam injection. Gillies said the first injection will provide a convenient hook for coverage, including a live BBC broadcast of the turn-on around 9:30 a.m. CET (3:30 a.m. ET) on the appointed day. However, he stressed that the beam injection was just one step in a months-long commissioning process.
“It’s not like launching a space shuttle or anything like that,” Gillies said.
The first low-power proton collisions would come later in the summer or fall, leading up to a VIP ceremony on Oct. 21. The collider won’t reach its full power until next year, after CERN’s winter break. Any legal questions should be resolved by the time the Large Hadron Collider gets anywhere close to post-big-bang energies. At least that’s what the Justice Department and CERN would expect.
Weighing the risksFor his part, Wagner wants to see the safety report first. Despite all the expert claims that the LHC will be safe, the former nuclear health physicist insisted that nothing he's seen so far has absolutely ruled out the black-hole doomsday scenario.
"For all I know, they will come up with some other novel argument that proves this can't happen. We want to see an argument that absolutely proves it ... because otherwise it ends up being [a statement that] 'we have no way of calculating.' And that, to me, is a scary proposition."
I should emphasize here that most scientists, even the ones who think way outside the box, are not scared. Here's how theoretical physicist Michio Kaku, the author of "Physics of the Impossible," put it to me back in February:
"I'm going to sleep well when that machine is turned on, because I know that cosmic rays have more energy than the Large Hadron Collider, and you don't see black holes from outer space. These are microscopic in size, and they don't last long."
Of course, there are always counterarguments, and counter-counterarguments. For a sampling, you can check out LHC Concerns and the BackReaction blog, among many other resources.

Tuesday, May 20, 2008

A fragment of DNA from the Tasmanian tiger has been brought back to life.


Australian scientists extracted genetic material from a 100-year-old museum specimen, and put it into a mouse embryo to study how it worked.
It is the first time DNA of an extinct species has been used in this way, says a University of Melbourne team.
The study, published online by the Public Library of Science (PLoS), suggests the marsupial's genetic biodiversity may not be lost.
Dr Andrew Pask, of the Department of Zoology, who led the research, said it was the first time that DNA from an extinct species had been used to carry out a function in a living organism.
"As more and more species of animals become extinct, we are continuing to lose critical knowledge of gene function and its potential," he said.
"Up until now we have only been able to examine gene sequences from extinct animals. This research was developed to go one step further to examine extinct gene function in a whole organism."

Genetic heritage
The Tasmanian tiger was hunted to extinction in the wild in the early 1900s. The last known specimen died in captivity in 1936, but several museums around the world still hold tissue samples preserved in alcohol.
The University of Melbourne team extracted DNA from some of these specimens, and injected a gene involved in cartilage formation into developing mouse embryos.
The DNA functioned in a similar way to the equivalent gene in mice, giving information about the genetic make-up of the extinct marsupial.
"At a time when extinction rates are increasing at an alarming rate, especially of mammals, this research discovery is critical," said Professor Marilyn Renfree, also of the University of Melbourne's Department of Zoology.
"For those species that have already become extinct, our method shows that access to their genetic biodiversity may not be completely lost."

Frozen Ark
Prof David Rawson, who was not part of the research team, said the work gave a glimpse of an aspect of an organism that we no longer have.
"We only get a glimpse; we only see a tiny part of the whole picture," he said.
Prof Rawson said the DNA came from a species that only recently died out, and for which there are samples preserved in alcohol. Going further back in time will be more difficult, he added.
"To go back to animals and plants that went extinct thousands of years ago, there is less chance to get a sizeable portion of DNA to unravel it," he explained.
"But modern techniques are developing all the time - we can now get information from material we once thought was impossible."
Some researchers think the method could help reveal the function of genes in species such as the Neanderthals or mammoths.
Prof Rawson, of the LIRANS Institute of Research at the University of Bedfordshire, UK, is one of several UK experts involved in the Frozen Ark, a global project to preserve genetic information from a range of threatened species.
Full details of the Australian study are published in the open-access journal PLoS One.

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